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[76] have developed a lipase-labile prodrug of fumagillin (Fum-PD) with Sn2 translatable moiety, which overcomes the photo-instability and enhances drug retention in circulation for improved delivery to angiogenic endothelial cells via CFDD
Introduction Ubiquitin has long been known to be associated with pathologies of the brain, including that of Alzheimers disease (AD
While maximizing the payload load, such a high and heterogeneous DAR profile is associated with increased hydrophobicity, elevated risk of aggregation, and accelerated plasma clearance, necessitating rigorous analytical control during development
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