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Vaca G, Armbula E, Monsalvo A, Medina C, Nuez C, Sandoval L, et al

However, in contrast to the robust metabolic and cardiorenal evidence base, evidence regarding reproductive outcomes, periconception safety, and offspring health remains limited and heterogeneous

Outside Russia, they are primarily used as research compounds

Both the GLP-1 and GIP receptors are expressed on neurons in the arcuate nucleus and other parts of the hypothalamus, and their activation reduce food intake and body weight ( These findings have promoted an interest to discover the CV benefits of this pharmacological class extending beyond its glycemic effect