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doi: 10.1056/nejmoa2301972
Hamlet Gasoyan, an investigator with the Cleveland Clinics Center for Value-Based Care Research
Oral formulations may be particularly appropriate for patients with documented needle anxiety or injection-related psychological barriers that would prevent injectable therapy initiation or continuation, individuals whose travel schedules, living situations, or daily routines make weekly injection protocols impractical, those seeking maximum medication discretion where tablet administration offers advantages, patients preferring oral medication based on personal autonomy and comfort considerations, and individuals willing to commit to strict daily dosing protocols required for adequate oral absorption
Severe gastrointestinal events led to discontinuation in approximately 6.4% of liraglutide users
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