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B12 functions as a cofactor in cellular metabolism but does not directly cause fat reduction or appetite suppression

It means it didn't work well enough as a standalone pharmaceutical drug

For example, people who maintain a vegetarian or vegan diet, people with absorption disorders, and those taking prescription meds like Metformin, Proton Pump Inhibitors (PPIs), and H2 blockers like Pepcid are often at greater risk

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