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Dietary Se is also included in the protection of the testis germ cells from oxidative stress, endoplasmic reticulum stress, and apoptosis by modifying extracellular signal-regulated kinase (ERK) and mitogen-activated protein kinase (MAPK) signaling (41, 158)
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This system, responsible for the degradation of damaged and unnecessary proteins through ubiquitin-mediated mechanisms, regulates numerous fundamental cellular processes
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