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Future perspectives in terms of nephro-protection in lupus nephritis Finerenone Novel MRA, like finerenone, are known to block MR-mediated sodium reabsorption and MR overactivation with additionally demonstrated anti-inflammatory and anti-fibrotic effects ( SGLT2i Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have recently been demonstrated to exert profound cardio and nephroprotection in large cardiovascular outcome trials ( via a glucose-independent hemodynamic mechanism
Multi-mechanism approaches can be more effective but also increase the risk of side effects and drug interactions
allow both to air dry completely [11]
doi: 10.1016/j.phrs.2021.105874 3
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