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It serves as a hub molecule that connects antioxidant defense, detoxification, immune signaling, and cellular metabolism

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Patients with a history of certain conditions , including pancreatitis, severe kidney disease, gastroparesis, or type 1 diabetes, should discuss risks carefully with their provider before starting treatment

This review was registered in Open Science Framework Systematic Review Registration: 1 Introduction The International Diabetes Federation (IDF) Diabetes Atlas (2025) indicates that 11.1% (or 1 in 9) of the population aged 20-79 is estimated to have diabetes, and more than 40% of that number does not have a diagnosis