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SCFAs stimulate L-cells to release GLP-1, while Akkermansia and mucosal-supportive microbes enhance enteroendocrine hormone sensitivity

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A modelbased metaanalysis of 24 antihyperglycemic drugs for type 2 diabetes: Comparison of treatment effects at therapeutic doses

Important differences from humans include the disproportionately large cecum, coprophagic behavior, standardized laboratory diets, and specific-pathogen-free housing conditions, all of which can substantially influence microbial composition and metabolic interactions