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doi:10.3390/ijms20010231
AOD 9604s evidence base comes primarily from animal studies Both peptides operate through entirely different biological mechanisms, making a direct comparison challenging AOD 9604 vs Tirzepatide: The Core Difference AOD 9604 is a modified fragment of human growth hormone (specifically amino acids 176-191 with an additional N-terminal tyrosine residue) engineered to isolate the lipolytic domain of hGH while avoiding broader growth hormone receptor activation
Side effects and safety profiles Safety is where AOD 9604 has its clearest advantage
Despite being a GH fragment, AOD9604 does not bind with high affinity to the HGH receptor and does not promote cell proliferation in HGH receptor-transfected cells
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