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Patients should be advised to: Rise slowly from lying or sitting positions, pausing briefly in a seated position before standing Maintain adequate hydration , particularly during periods of gastrointestinal side effects Avoid prolonged standing , especially in warm environments or after large meals Wear compression stockings (if appropriate and tolerated) to improve venous returnthese should be properly fitted and avoided in patients with significant peripheral arterial disease Elevate the head of the bed by 1020 degrees to reduce nocturnal diuresis and morning hypotension Consider dietary salt intake only under clinician supervision and if not contraindicated by heart failure, hypertension or renal disease Medication review is essential

[3] At the 12 mg dose, the mean weight reduction was about 17.5% at 24 weeks (the primary endpoint) rising to roughly 24.2% at 48 weeks , compared with about 2.1% for placebo

GRPP: glicentin-related pancreatic polypeptide

Skin Brightening & Glow: Promotes an even skin tone and reduces hyperpigmentation