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Statins and Treg cells There is increasing evidence aiding understanding of the mechanisms behind the immunomodulatory effects of statins from in vivo and in vitro investigations

19 High tumor mutational burden (TMB), 20,21 microsatellite instability (MSI-H), 22 and mismatch repair deficiency (dMMR) 23 are associated with enhanced neoantigen presentation and improved responses to immune checkpoint inhibitors (ICIs)

Both sit squarely at the intersection of metabolic medicine and the booming longevity industry

Additionally, inflammatory conditions are also suggested to benefit due to its regenerative and protective properties