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Antibody-drug conjugates normally employ cytotoxic agents as payloads, but many of them are substrates of the efflux transporter MDR1, which is an important mechanism to generate drug resistance
Increased glycosaminoglycan synthesis : Reviewed in Pickart & Margolina 2018, supporting structural hydration capacity
*The benefits of IV and IM therapy described here are based on broad observations and may not apply to everyone
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