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Systemic dosing is based on research models
Method development and assay calibration: Use of the Ipamorelin / CJC-1295 blend as a reference tool in assay development, bioanalytical method validation and mechanistic GH secretion research in vitro and in vivo
In previous GLP-1- or exendin-P5-bound active structures 3,4 , the ECD shows a fully extended open conformation, whereas in the peptide 5-bound active-like structure 12 , the ECD is less extended since it makes fewer interactions with the truncated peptide 5
The datasets were combined for analysis
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