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Interestingly, L-NAME administration significantly abolished the initial peak of the triphasic pattern (15 s, HbT in pre/post-L-NAME: 7.04 1.90/4.73 0.55%, n = 4 mice, p = 0.0089, paired sample, two-tailed t test), and slightly reduced, albeit insignificantly, the late vasodilation under awake conditions (2635 s, HbT in pre/post-L-NAME: 19.11 3.04/11.16 2.10%, n = 4 mice, p = 0.1293, paired sample, two-tailed t test) (Fig

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