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Autophagy 16 (8), 14531467
49 Elevated inflammatory factors in T2D such as IL-6 and interferon- (IFN-) cand bind to their receptors, activate JAK2/STAT3, subsequently upregulates the expression of suppressor of cytokine signaling 3 (SOCS3), which inhibit IRS-1 cascade
Research suggests that activation of these receptors may increase hunger cues and could contribute to changes in body composition, including potential increases in adiposity
This is the strongest piece of evidence in Dihexa's favor, and it is important to frame it accurately: it is a small rodent study in a disease model, not a human trial, and not a measure of cognitive enhancement in healthy people
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