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The potent neuro-protective ability of Sp was mainly derived from its ability to maintain glutathione levels in its oxidizable form, possibly by preventing its catabolism, though the exact chemical mechanism needs to be elucidated through further studies

Astrocytes also show heterogeneity by reflecting inflammatory and metabolic changes

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Astrocytes, the brains immune cells, may produce enormous amounts of ketone bodies, which are thought to provide nearby neurons with easily transportable substrates for energy synthesis