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Efficient uptake of iodine, selenium, iron, and zincmicronutrients governing thyrocyte function from hormone synthesis (iodination, TPO activity) to peripheral activation (DIO-mediated T 3 generation)serves as a therapeutic target in hypothyroidism and Hashimotos thyroiditis, particularly in populations with coexisting deficiencies (Shulhai et al., 2024)
(ii) total, selenium-containing, and non-selenium glutathione peroxidase (GPx) levels
The observed sex-specific effects highlight the necessity of designing treatments that account for sex differences in neurodegenerative and metabolic diseases, considering that females are disproportionately affected by both Alzheimers disease and obesity
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