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Human safety data is limited, and long-term effects remain unknown
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Results : Among 66 patients (47 adults and 19 children), ALD was observed in 26/47 (55.3%) of adults and 13/19 (68.4%) of children
predicting phenobarbital level based on loading dose Level ~ 1.5 [ Dose in mg/kg ] For every 1 mg/kg of phenobarbital administered, the serum phenobarbital level will rise by roughly ~1.5 mg/L (e.g., 10 mg/kg will increase the phenobarbital level by 15 mg/L)
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