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Overall, these findings are complementary to results in a companion article 57 , in which the body-weight-reducing and food-intake-reducing effects of GIPR antagonism are disrupted in mice with global loss of either Gipr or Glp1r but preserved in mice with loss of Gipr in either GABAergic or peripheral neurons
A pilot study investigating gut microbiomes of 52 patients receiving either Dulaglutide or Liraglutide determined a microbial signature of GLP-1RA responders ( n = 34) and non-responders ( n = 18) (Tsai et al., 2022)
Ethics declarations Ethics approval and consent to participate The datasets generated and/or analyzed during this study are not publicly available because they are stored on the corresponding author's personal account on the Stampede3 supercomputer
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