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Furthermore, many studies report improved mitochondrial function based on a limited set of parameters (e.g., ATP, MMP)
the triad model is simpler, requiring estimation of fewer parameters
Even with large scale populational and longitudinal studies, gaining a better understanding of these factors and their interactions remains a challenge (111, 158)
The role of mTORC2 in the regulation of autophagy is less investigated than mTORC1
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