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GLP-1 Persistence is Crucial for Outcomes and ROI A: Medication persistence refers to the patient's ability to stay on the treatment over the prescribed length of time, and is a crucial factor in achieving intended health outcomes
Clinical trials (SURPASS) have demonstrated that tirzepatide reduces hemoglobin A1c by 1.9% to 2.4% depending on dose, with much of this benefit attributable to enhanced glucose-dependent insulin secretion and suppressed glucagon release
This mechanism would bypass the gastrointestinal tract and provide steady-state drug levels over an extended period
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