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An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of phase II and III clinical trials
Loading phase uses higher doses (2.5-5mg) 2x weekly for 4-6 weeks to rapidly saturate tissues and initiate healing
The most common were nausea, vomiting, diarrhea and constipation
Supplementing iron, particularly if severe deficiency is diagnosed, can help alleviate these symptoms and improve appetite
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