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Marked increase in severe neurological disorders after nitrous oxide abuse: a retrospective study in the Greater Paris area
In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
It also means watching and adjusting treatment plans closely
Lead author, Dr Natasha Tyler said: Patients with vitamin B12 deficiency often report feeling marginalised and describe their interactions with primary care as battles and report feeling stigmatised
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