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Caspase-3 activities were measured with commercial kits according to the manufacturers recommendations (Abcam, AB39401)
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These results indicate that cagrilintides metabolic effects are receptor-dependent and that functional AMY1R/AMY3R signaling is essential for proper nutrient partitioning and energy balance regulation
doi: 10.2337/dc12-1925 26 FriedrichsenMBreitschaftATadayonSWizertASkovgaardD
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