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Notably, the proportion stopping treatment because of side effects (7%) was barely above placebo (6%) closer than usual for this class
Its mechanism of action appears to be partly similar to established agents such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), but retatrutide targets three receptors at once
Novo Nordisk (2018) Ozempic (semaglutide) approved in the EU for the treatment of type 2 diabetes
Cortical bone demonstrated elevated porosity and reduced tibial cortical thickness, resulting in declines of 5.7%, 5.5%, and 5.2% in tibial compressive strength, stiffness, and apparent modulus, respectively
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