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Therapeutic Research Protocol Dose: 1.0 2.0 mg (= 2040 clicks) Duration: 3 6 weeks Frequency: Daily until target pigmentation observed Cycle Interval: 4 6 weeks off before repeating Goal / Description: Higher-dose schedule used in photoprotection and MC1R activation studies
10.1053/j.gastro.2008.01.073 Gastroenterology 117 MariM.ColellA.MoralesA.von MontfortC.Garcia-RuizC.Fernandez-ChecaJ
As a context, genes potentially impacted by melanocortin signaling include those involved in microglial activation, cell metabolism, protein processing, stress responses, responses to misfolded proteins, and pathways involving transforming growth factor-beta (TGF-)
The Journal of cell biology, 1994, 125(4): 929- 943
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