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Conformational biosensors reveal GPCR signalling from endosomes

Diabetic patients with conventional subcutaneous insulin therapy had lower IGF-1 levels than patients with continuous subcutaneous insulin infusion and intraportal insulin infusion [13]

In vivo, cLip-1 increased the survival of mice in which acute renal failure was induced through genetic deletion of Gpx4 , which encodes the ferroptosis suppressor glutathione peroxidase 4 (GPX4) 2 (Fig