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358 For ferroptosis, which represents a therapeutically actionable vulnerability, restoring iron-dependent lipid peroxidation is key
It supports and maintains cellular health by destroying free radicals that contribute to oxidative stress and promote detoxification within the body
Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8 + T cells in tumors
Falutz J, Mamputu JC, Potvin D, Moyle G, Soulban G, Loughrey H, Marsolais C, Turner R, Grinspoon S
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