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Toxic accumulation of Amyloid protein, commonly associated with Parkinsons Disease (27), disrupts Long Term Potentiation (LTP) (24)
Escalation to the next dose level occurred following satisfactory Safety Review Committee review of available safety data up to day 4 and available pharmacokinetic data from all participants at that dose level
Biotransformation and elimination may also be impaired, leading to poor detoxification and recirculation of toxins that worsen symptoms
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