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15 Mice lacking the clock genes Per1/2 and Cry1/2, or deficient in BMAL1, have a greater likelihood of developing hepatocellular carcinoma
The Hyperhidrosis Disease Severity Scale The Hyperhidrosis Disease Severity Scale [7] is a four-point questionnaire to assess the impact of the condition on a patients daily life by selecting from the following 4 options [8]: My sweating is never noticeable and never interferes with my daily activities My sweating is tolerable but sometimes interferes with my daily activities My sweating is barely tolerable and frequently interferes with my daily activities My sweating is intolerable and always interferes with my daily activities
doi:10.3390/biom11020217 Bach LA, Hsieh S, Sakano K, Fujiwara H, Perdue JF, Rechler MM
This comparison highlights the trade-off between proven clinical validation and mechanistic advancement
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