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It is classified as a triple hormone receptor agonist, which means it activates three separate hormone pathways in the body at the same time
Cortisol patterns can become disrupted when the body perceives itself to be in an energy-restricted state
The tablet uses a graduated dosing schedule, starting at 1.5mg daily and stepping up over several months to 25mg
Eligibility is restricted to adults with a BMI of at least 35 kg/m and at least one weight-related comorbidity, or a BMI of 40 or above, who have not achieved meaningful weight loss through nutritional management, and who are under specialist supervision with a lifestyle programme
