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This paradigm shift operates through: (i) dual-function targeting (simultaneous antithrombotic action and regenerative promotion), (ii) spatiotemporal inflammatory reprogramming (controlled macrophage polarization), and (iii) synergistic regenerative factor delivery (orchestrated release of cardioprotective mediators) [62, 94](Fig
MAFLD is also referred to as metabolic dysfunction-associated steatotic liver disease, MASLD
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