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Yan W, Chen X
Even at doses 200-fold above the effective GH-releasing dose, ipamorelin did not stimulate cortisol demonstrating a true selectivity threshold rather than merely a dose-separation effect
Large cardiovascular outcome trials have demonstrated that several agents in this class reduce major adverse cardiovascular events (MACE) in patients with type 2 diabetes, with benefits extending beyond just those with established cardiovascular disease in some trials
This synthetic analog has a 13-amino acid N-terminal extension and an arginine substitution at position 3, replacing the original glutamic acid residue
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