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doi: 10.1158/1055-9965.EPI-19-1027 5 Karam-HageMCinciripiniPMGritzER

These symptoms may indicate pancreatitis, a serious but rare adverse effect, or severe dehydration requiring intervention

Other risk groups include older adults, pregnant women, people taking metformin or long-term acid-suppressing medications (PPIs, H2 blockers), those with conditions affecting the gastrointestinal tract (pernicious anaemia, Crohn's disease, coeliac disease), and individuals who have undergone gastric or ileal surgery