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In this global registration trial, where 84.0% of participants had a baseline BMI of 35 kg/m, each dose of retatrutide (9 mg and 12 mg) met all primary and key secondary endpoints, delivering significant weight loss and improvements in pain and physical function at 68 weeks using both the efficacy and treatment-regimen estimands
Zbyt duy deficyt energetyczny zwiksza rwnie ryzyko efektu jojo po zakoczeniu leczenia
however, indirect effects such as increased heart rate, gastrointestinal distress, or hypoglycaemia may provoke anxiety-like symptoms in susceptible individuals
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