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2020;641-647.e3
Retatrutide appears to have a similar safety profile to other GLP-1 medications: No increased risk of pancreatitis in trials so far No hepatotoxicity signals (liver damage) No cases of ketoacidosis Serious adverse events were rare (2.5% of participants) The trials are ongoing, so we'll learn more about long-term safety
Following this international signal (an adverse event that is potentially caused by a medicine that warrants further investigation), the TGA asked its Advisory Committee on Medicines for independent expert advice
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