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Examining hepatic gene expression and histology in vivo corroborates FGF21s direct inhibition of fibrosis arising from liver injury induced by diverse insults
This limitation of standard lab testing approaches stems from how reference ranges are calculated
In its reduced form (GSH), glutathione can regenerate itself in the liver after each interaction with a free radical, ready to neutralise another
Dysbiosis in the gut similarly disrupts barrier integrity, increasing intestinal permeability (leaky gut) and allowing endotoxins to enter circulation while reducing beneficial SCFA-producing microbes
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