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Its often overlooked, but some of the most cited clinical trials of GLP-1s (like the SELECT and SURMOUNT trials) included lifestyle interventions

The medication works in the following ways: Reduces hunger signals in the brain Slows stomach emptying so you feel full longer Helps control blood sugar levels Reduces cravings and food noise Because of these effects, many patients naturally eat fewer calories and gradually lose weight

Alan Rogol, Professor Emeritus of Pediatrics and Pharmacology at the University of Virginia, has noted: "Growth hormone secretagogues operate on a fundamentally different axis than monoaminergic antidepressants

Both medications require several months to achieve maximum efficacy