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In a rat model of IBS, intraperitoneal administration of exendin-4 normalized stress-induced defecation and visceral pain sensitivity by modulating enteric neuronal function through GLP-1 receptors in submucosal and myenteric ganglion neurons [52]
Serious side effectssuch as signs of pancreatitis, severe abdominal pain, or gallbladder issuesrequire immediate medical attention and should prompt communication with your healthcare team
Stasi, R
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