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A systematic review comparing these medications found that retatrutide (12 mg) achieved 22% weight loss from baseline, compared to 18% for tirzepatide and 14% for semaglutide
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Why this matters: Prevents headaches Reduces nausea intensity Supports digestion and bowel movement What to do: Drink water consistently throughout the day Increase intake if you feel fatigued or dizzy Add electrolytes if needed (especially during low food intake) Common mistake: People eat less but forget to drink more 4
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