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Dose and Duration of treatment

Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) represent unique cases of infection-triggered brain autoimmunity

Furthermore, a comprehensive review published in the Journal of Translational Medicine proposed a unifying model for ME/CFS and Long COVID, highlighting how viral infections (like SARS-CoV-2 or Epstein-Barr Virus) trigger a cascade of immune exhaustion, micro-clotting, and severe oxidative stress

Acute symptoms such as fatigue may improve within days, whilst neurological symptoms like paraesthesia typically require weeks to months of treatment