The Daily Reality of Taking Oral GLP-1 Oral GLP-1 requires a specific administration protocol that patients should understand before starting: Taken first thing in the morning With no more than 4 oz (120 mL) of plain water On a completely empty stomach With no food, beverages (including coffee), or other oral medications for at least 30 minutes afterward This routine works well for patients who can build it into their mornings without friction
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doi: 10.1111/sms.13592 89 MontuoriPLopertoIPaoloCDi DatoCDe RosaACirilloTet al
Crabtree T, Ogendo JJ, Vinogradova Y, Gordon J, Idris I (2022) Intensive glycemic control and macrovascular, microvascular, hypoglycemia complications and mortality in older (age 60years) or frail adults with type 2 diabetes: a systematic review and meta-analysis from randomized controlled trial and observation studies