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Research Summary IGF-1 LR3 is a recombinant long arginine analog of insulin-like growth factor 1 with a 13 amino acid N-terminal extension that reduces IGF-binding protein affinity, resulting in a ~120-hour half-life versus 15 hours for native IGF-1

Uncontrolled hyperthyroidism can affect heart rate and cardiovascular function, which should be stable before adding medications that affect metabolism and weight

Certain medical conditions or medications may contraindicate the use of vitamin IV drip therapy

While the brand name Zepbound is relatively new to the market, the underlying science and the active molecule have a history that extends back several years