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Unlike other drugs such as Mounjaro and Zepbound, which activate both GLP-1 and GIP receptors, MariTide works as a GLP-1 receptor agonist and a GIP receptor antagonist

AOD-9604 differs from GLP-1 agonists in both structure and mechanism: its a 16-amino-acid fragment of growth hormone theorized to act directly on fat cells, whereas GLP-1 agonists like Semaglutide work by activating GLP-1 receptors to influence insulin release, gastric emptying, and satiety

This peptide operates at a molecular level, interacting with various pathways to facilitate optimal health outcomes

The two compounds illustrate how diverse the broader GH research peptide field is same biological axis, completely different research mechanisms