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The origin itself explains the historical direction of research: the first area described was cytoprotection of the gastric and intestinal mucosa, and only later did the literature broaden the molecules profile to include angiogenesis and soft-tissue repair
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[1] The name islet amyloid polypeptide reflects a defining quirk: in humans, amylin has a strong tendency to aggregate into insoluble amyloid fibrils, and deposits of these fibrils are commonly found in the pancreatic islets of people with type 2 diabetes
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