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In the in vivo experiments, the authors treated the streptozotocin-induced DM mice with exendin-4 at 10 nmol/kg for 4 weeks and found that exendin-4 promoted the peripheral nerve function as reflected by improved current perception threshold and motor and sensory nerve conduction velocity
If metformin-associated lactic acidosis is suspected, immediately discontinue JANUMET and institute general supportive measures in a hospital setting
This product is designed for investigation of: Glucose metabolism regulation Appetite and satiety mechanisms Weight management pathways Cardiovascular health markers Storage: Store lyophilized peptide at -20C
The distribution and partition coefficients are in general agreement with the pK a of sitagliptin (7.7) (Charoo NA, et al ., 2022)
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