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When combined, patients should be monitored for cumulative side effects, though these typically reflect the individual safety profiles rather than synergistic toxicity

Never inject into areas that are bruised, tender, or scarred from previous injections

The gut hormone glucagon-like peptide-1 (GLP-1) and its analogues, which have been in clinical use for diabetes for over a decade, have useful appetite-suppressive effects and are now licensed for obesity