Clin Ther 29(1):139153 Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH et al (2009) Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
Ispaghula husk is a soluble fibre licensed in the UK for constipation relief and cholesterol reduction, typically dosed at 3.5 grams twice daily with adequate fluid
Return to heavier activity, forceful gripping, and physical work is typically 46 weeks
FIGURE 2 2.1.1 Calcium channel modulation Recent research has shown that exendin-4, a GLP-1RA, suppresses L-type voltage-gated calcium channels (L-VGCC) activity through a cascade involving cAMP/PKA, ryanodine receptors, and calmodulin (CaM)