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Moreover, the meta-analysis of Boushey et al (1995) indicates that a daily folate supplement at doses as low as 400 g may induce a 6 mol/L decrease in plasma homocysteine and prevent 28,000 deaths per year by myocardial infarction
It has also been shown that pollutants affect the metabolism of isolated human cells which in turn resulted in highly increased oxidative stress levels and consequently cell damage and reduced cell activity leading to cell death
The precise mechanism(s) by which low GSH induces CYP2E1 and ALDH1A1 remain to be elucidated
& Jozefczak, M
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