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Laboratory studies may show evidence of massive hepatic necrosis with elevated AST, ALT, bilirubin, and prolonged coagulation times (in particular, elevated prothrombin time)
These alternatives can provide similar benefits without the potential adverse effects on glutathione levels
In the SURPASS-2 diabetes trial, an open-label 40-week study randomised 1,879 patients with type 2 diabetes to tirzepatide 5, 10, or 15 mg or to semaglutide 1 mg
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